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Updated: Jan 8, 2026

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
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Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors

Published on: August 5, 2022

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可通过表观遗传药物向MECP2-依赖性癌症:表观遗传癌症治疗的新作用

Manish Neupane1, Mukesh Kumar2, Malela A Mwamufiya3

  • 1MSD (United States) Rahway, NJ United States.

Molecular cancer therapeutics
|December 11, 2025
PubMed
概括

甲基CpG结合蛋白2 (MECP2) 作为一种瘤基因. 针对MECP2的表观遗传疗法对MECP2过度表达的癌症有希望,揭示了一种新的药物机制.

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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts10:27

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

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