越南痴呆症诊断后的多药制:在门诊环境中使用现实数据的结果
Gerontology
|December 11, 2025
概括
这项研究发现,越南的痴呆症患者,特别是患有血管痴呆症的人群中,多药 (使用5种或更多药物) 是常见的. 在这个群体中,潜在不合适的药物更常见,这突显了需要谨慎处方的必要性.
科学领域:
- 老年学是一门学科.
- 临床药房 临床药房
- 流行病学 流行病学
背景情况:
- 痴呆症患者的多药性与不良结果有关,包括认知和身体障碍.
- 虽然在全球范围内进行了研究,但越南痴呆症人口中的多药流行病学仍未得到研究.
研究的目的:
- 调查越南痴呆症患者中多药学的流行病学.
- 在这个人群中识别与多药学相关的风险因素.
主要方法:
- 越南国家老年医院诊断出痴呆症的门诊患者的一项回顾性队列研究.
- 从医疗记录中提取了有关药物使用,并发症和社会人口统计数据的数据.
- 多药性定义为每月≥5种药物;使用Beers标准评估的潜在不合适药物.
主要成果:
- 64名患者 (平均年龄为73.5,女性为68.8%) 观察到多药性.
- 与阿尔茨海默病相比,血管痴呆和其他类型的痴呆症的多药性几率显著更高.
- 严重的痴呆阶段与较低的多药发生率有关;在多药组中,潜在不合适的药物更为普遍.
结论:
- 越南痴呆症患者中多药的发生率可能低于之前的研究,可能是由于药物管理改善或低估.
- 需要进一步的研究来了解多药对痴呆症患者健康结果的影响.
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