在儿科急诊室的位温度和败血症干预的及时性
McKenna Straus1, John M Morrison1,2, Racha Khalaf3
1Johns Hopkins All Children's Hospital, Office of Medical Education, St. Petersburg, Florida.
The western journal of emergency medicine
|December 11, 2025
概括
呈现低温 (温度≤36.0°C) 的败血症儿童的结果更差,包括增加死亡率和器官功能障碍. 然而,败血症生理发作的温度 (PO-S) 并没有影响抗生素或液体玻尿酸注射的时间.
科学领域:
- 儿科急救医学 儿科急救医学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 发烧通常是感染的信号,促使急诊室 (ED) 评估败血症.
- 在成年人中,败血症呈现期间的正常温度与延迟治疗和较高的死亡率相关.
- 儿科ED的温度和败血症护理及时性之间的关系尚未得到充分理解.
研究的目的:
- 为了研究体温在体质发作性败血症 (PO-S) 的身体温度和在儿童中抗生素和液体玻尿酸注射的时间之间的联系.
- 为了确定PO-S的温度是否会影响儿科败血症的关键结果.
主要方法:
- 在ED的儿科败血症患者的回顾性队列研究.
- 在PO-S时评估体温,定义为第一次满足临床败血症标准.
- 分析了使用多变量定量回归的抗生素/液体的时间,死亡率,器官功能障碍以及ICU/医院无病日.
主要成果:
- 在不同温度组 (低温,正常热,发烧) 中,在服用抗生素或液体玻尿酸的中位时间中没有显著差异.
- 在PO-S中患有低温症 (≤36.0°C) 的儿童在72小时 (68.2%) 后的死亡率 (4.5%) 和器官功能障碍显著增加.
- 与正常热或发烧儿童相比,低温儿童也经历了较少的ICU和不入院日.
结论:
- 在PO-S时的体温没有影响儿科败血症中抗生素或液体玻尿酸输送的及时性.
- 患有低温症的儿科败血症患者面临较差的临床结果,包括增加的死亡率和器官功能障碍.
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