对患有固体甲状腺结节的儿童的评估:单中心体验
Ömer Günbey1, Firdevs Dilara Paksoy1, Nurdan Yıldırım Acar1
1Medical School, Department of Pediatrics, Division of Endocrinology, Fırat University, Elazig, Türkiye.
Journal of pediatric endocrinology & metabolism : JPEM
|December 11, 2025
概括
儿童甲状腺结节需要仔细评估. 超声波和贝塞斯达细胞学是关键,但如果超声波显示可疑特征,即使有良性结果,也可能需要手术.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 在瘤学瘤学.
- 诊断成像 诊断成像 诊断成像
背景情况:
- 甲状腺结节在儿童中比成年人少,但携带恶性瘤的风险更高.
- 准确诊断儿科甲状腺结节对于适当的管理至关重要.
研究的目的:
- 分析儿科患者固体甲状腺结节的细胞病理学和细胞病理学特征.
- 评估超声波 (US) 在这些结节中发现的诊断效用.
主要方法:
- 对53名患有固体甲状腺结节的儿科患者进行了回顾性审查,这些患者接受了活检.
- 使用贝塞斯达系统对活检结果进行分类.
- 对暗示恶性瘤的超声波特征的评估.
主要成果:
- 大多数患者是女性 (81.1%),平均年龄为16.1岁.
- 贝塞斯达的类别包括良性 (47.2%),非诊断性 (24.5%) 和可疑/恶性 (9.4%).
- 乳头甲状腺癌 (PTC) 在接受手术治疗的患者中被诊断为63.2%,通常有多个可疑的美国发现. 在两名患有良性细胞学的患者中也发现了PTC.
结论:
- 甲状腺结节恶性瘤的风险在儿童中更高,需要综合诊断方法.
- 手术决策应结合超声波风险评估和贝塞斯达细胞学.
- 考虑对多个可疑的美国特征的结节进行手术,即使是良性或不确定的细胞学.
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