尾癌是非手术治疗儿科无并发尾炎的风险吗?
Alexa G Turpin1, Lindsey Asti1, Carley Lutz2
1Nemours Surgical Outcomes Center and Department of Surgery, Nemours Children's Health, Delaware Valley, Wilmington, Delaware.
The Journal of surgical research
|December 11, 2025
概括
儿科尾炎的非手术治疗是常见的. 这项研究发现,在符合非手术治疗标准的儿童中,尾癌非常罕见,这表明它应该对治疗决策的影响最小.
科学领域:
- 儿科手术 儿科手术
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
背景情况:
- 儿童无并发性尾炎的非手术治疗 (NOM) 越来越多地被使用.
- 有一个理论上的风险存在于缺失随机尾癌与NOM,因为它经常被诊断为尾切除术后.
研究的目的:
- 为了确定适合NOM的儿童尾癌的发病率.
- 评估NOM在错过的尾恶性瘤方面的安全性.
主要方法:
- 一项多机构试验的二次分析,将手术与NOM进行比较,用于儿童 (7-17岁) 无并发性尾炎.
- 纳入标准:成像证实无并发性尾炎,特定白细胞计数,疼痛持续时间<48小时.
- 进行尾切除术的病理学审查,包括那些经过失败的NOM后,以确定尾癌.
主要成果:
- 826名患者接受了尾切除术;128名患者在失败后进行了NOM.
- 有824名患者的病理学报告.
- 没有发现尾癌的病例 (95% CI: 0%-0.36%).
结论:
- 在符合NOM标准的无并发尾炎的儿童中,尾癌非常罕见.
- 对这些患者来说,尾癌的风险应对NOM和手术之间的决策过程产生最小的影响.
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