在患有多发性硬化症的个体中,睡眠和体力活动的客观测量之间的关联
Adi Einav-Farber1, Shay Menascu2, Tali Drori2
1Department of Physical Therapy, School of Health Professions, Gray Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel.
Multiple sclerosis and related disorders
|December 11, 2025
概括
身体活动可以改善患有多发性硬化症 (MS) 的人的睡眠质量. 客观测量显示,更好的睡眠效率与更高的每日步数相关,即使考虑到移动性问题.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 康复科学 康复科学 康复科学
背景情况:
- 睡眠障碍在患有多发性硬化症 (pwMS) 的人中很普遍,对生活质量产生负面影响.
- 以前的关于pwMS睡眠和体力活动的研究经常忽视了诸如抑郁症和移动性问题之类的混因素.
- 需要对睡眠和活动进行客观测量,以准确评估pwMS中的关系.
研究的目的:
- 调查pwMS中客观睡眠指标和身体活动水平之间的关联.
- 在分析中控制移动性,疲劳和心理健康等混因素.
- 为了确定睡眠指标在pwMS中预测身体活动的程度.
主要方法:
- 一项涉及50名pwMS (年龄在25-55岁) 的横截面研究,他们戴着ActiGraph加速度计七天.
- 使用加速度计数据对身体活动和睡眠模式进行客观评估.
- 评估的混变量包括移动性 (定时上路,四方步骤测试,MSWS-12),疲劳 (MFIS) 和心理健康 (HADS).
主要成果:
- 睡眠效率与每日步数和最大连续步数有显著的积极关联.
- 睡眠指标解释了16-17%的身体活动差异,在调整移动性和残疾后增加到30-35%.
- 客观的睡眠质量与pwMS中的客观体力活动措施有关.
结论:
- 促进体育活动可能是改善多发性硬化症患者睡眠质量的可行策略.
- 客观数据证实了pwMS中更好的睡眠和更高的体力活动水平之间的联系.
- 进一步的研究应该探索加强身体活动以改善MS管理中的睡眠改善的干预措施.
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