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Updated: Jan 8, 2026

Chronic Social Defeat Stress in Early Adolescent Male Mice
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Syntaxin 1A 同表达网络和童年创伤对成人抑郁症状的性别特异相互作用效应

Danusa Mar Arcego1, Carla Dalmaz2, Irina Pokhvisneva1

  • 1Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada, H4H 1R3.

EBioMedicine
|December 11, 2025
PubMed
概括

早期的创伤影响了抑郁症的风险,特别是在女性身上. 前额叶皮层中的一个特定的基因表达分数 (PFC-ePRS-STX1A) 可以缓解这种风险,突出突出突触可塑性.

关键词:
在阿尔斯帕克 (ALSPAC) 地区.抑郁症 抑郁症 抑郁症早期生活中的逆境.前额叶皮层前额叶皮层.在STX1A中,它是STX1A.英国生物银行

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