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Updated: Jan 8, 2026

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通过抑制炎症信号和细胞应激通路,通过蛋白质稳定调节改善RIPK3缺乏的糖尿病缩症

Jia Yi1, Jitai Zhang1, Xingxing Fang2

  • 1Jiangsu Key Laboratory of Tissue Engineering and Neuroregeneration, Key Laboratory of Neuroregeneration of Ministry of Education, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu Province 226001, PR China.

Biochemical pharmacology
|December 11, 2025
PubMed
概括

受体相互作用蛋白激酶3 (RIPK3) 通过破坏肌肉蛋白质稳定和增加炎症来驱动糖尿病. 抑制RIPK3显示出治疗这种糖尿病并发症的前景.

关键词:
慢性炎症是一种慢性炎症.糖尿病的萨尔科佩尼亚.氧化应激是一种氧化应激.蛋白质的平衡是蛋白质的平衡.在RIPK3中使用RIPK3.

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