环素E1作为瘤发生的驱动因素;高等级的血清性卵巢癌作为一个示例

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Updated: Jan 8, 2026

Heterotypic Three-dimensional In Vitro Modeling of Stromal-Epithelial Interactions During Ovarian Cancer Initiation and Progression
12:42

Heterotypic Three-dimensional In Vitro Modeling of Stromal-Epithelial Interactions During Ovarian Cancer Initiation and Progression

Published on: August 28, 2012

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Sarah J Taylor1, Charlie Gourley1

  • 1Nicola Murray Centre for Ovarian Cancer Research, Cancer Research UK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom.

Critical reviews in oncology/hematology
|December 11, 2025
PubMed
概括

环素E1过度表达通过引起基因组不稳定性驱动癌症. 针对CDK2和WEE1等细胞循环调节剂,显示出治疗癌症的前景,包括高度血清性卵巢癌 (HGSOC).

关键词:
在CCNE1中,细胞循环的细胞周期循环环 E E 循环环基因组不稳定性 基因组不稳定性在HGSOC中,HGSOC是什么?卵巢癌是发生在卵巢中的癌症.有针对性的治疗方法.

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