通过快速循环诊断-PASEF方法的保留时间下方采样来增强识别和量化

Christopher R Below1, Oliver M Bernhardt1, Stephanie Kaspar-Schönefeld2

  • 1Biognosys AG, Schlieren, Switzerland.

概括

在timsTOF HT上优化对角-PASEF与保留时间总和 (RTsum) 显著提高了蛋白质组量化. 与标准方法相比,这种新的方法可以改善信号噪声比率,并增加和蛋白质的识别.

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