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Updated: Jan 8, 2026

Efficient Gene Knockdown in the Liver via Intrasplenic Injection of Adeno-Associated Virus Serotype 8 (AAV8)-Delivered Small Hairpin RNA
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在AAV介导的B型血友病基因治疗中肝功能障碍:机制和管理策略

Xuewen Song1, Bingjie Ding1, Hongkai Jia2

  • 1The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China.

Blood reviews
|December 11, 2025
PubMed
概括

使用腺相关病毒载体治疗B型血友病的基因治疗显示出有前途,但可能导致肝脏问题. 仔细监测和免疫抑制是管理这些副作用的关键.

关键词:
在AAV基因疗法中,AAV基因疗法血友病B型 血友病B型 血友病B型免疫抑制是一种免疫抑制.肝脏功能障碍 肝脏功能障碍

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