在接受动脉内化疗的视网膜母细胞瘤患者的术前MRA
Marco Colasurdo1, Evgeny Pavlushkov2, Huanwen Chen3
1From the Department of Interventional Radiology (M.C., G.N.), Oregon Health and Science University, Portland, Oregon mcolasurdo@gmail.com.
AJNR. American journal of neuroradiology
|December 11, 2025
概括
在手术前的MRA准确地识别了儿科视网膜母细胞瘤患者的眼动脉变异和中脑膜动脉异构,有助于进行动脉内化疗.
科学领域:
- 儿科瘤学 儿科瘤学
- 干预性放射学是干预性的放射学.
- 眼科医生 眼科 眼科
背景情况:
- 动脉内化疗 (IAC) 对儿科视网膜母细胞瘤 (RB) 是至关重要的.
- 眼动脉 (OA) 通过内动脉 (ICA) 进入眼动脉可能具有挑战性.
- 中间脑膜动脉 (MMA) 到OA解剖形成提供了一个替代路线.
研究的目的:
- 评估手术前MRA检测OA变体的能力.
- 评估MRA在识别MMA-to-OA/眼动脉 (LA) 解的准确性.
- 确定MRA发现是否提高了儿科RB的IAC交付成功.
主要方法:
- 对接受IAC的儿科RB患者的回顾性审查 (2018年10月 - 2025年1月).
- 使用手术前MRA评估OA起源和MMA-OA解.
- 通过数字减去血管学 (DSA) 确认发现.
主要成果:
- 分析了13名患者 (42项手术);中位数年龄为11个月.
- 在92%的病例中,MRA可视化了OA的起源,而在46%的病例中,MMA-OA/LA解剖.
- 所有MRA检测到的瘤被DSA证实;其中50%用于IAC交付.
- 总体而言,程序成功率为98%.
结论:
- 术前MRA对于识别OA变体和MMA-OA解瘤是非常准确的.
- MRA有助于优化儿科RB的IAC交付.
- 使用MRA可能有助于尽量减少治疗期间的辐射暴露.
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