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Updated: Jan 8, 2026

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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转录因子和cBAF之间的共缩选择性地调节染色体重塑和基因表达

Xifu Ye1,2, Lin Xu1,2, Xuejiao Sun1,2

  • 1Department of Gastroenterology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.

Nature communications
|December 11, 2025
PubMed
概括

ARID1A是一种染色体重塑子单元,利用氨酸残留物以转录因子 (TF) 形成凝聚物. 这种选择性联合凝结对于基因激活和肺癌细胞增殖至关重要.

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