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在骨关节炎中识别和验证与棕化代谢相关的生物标志物,使用转录组和单细胞RNA测序分析

Dongliang Zhang1,2, Xin Liu1,2, Wei Zhang1,2

  • 1Tianjin union medical center, Tianjin Medical University, Tianjin, China.

Scientific reports
|December 11, 2025
PubMed
概括

研究人员确定BUB1B和KIF15是骨关节炎 (OA) 的关键生物标志物,这是一种退行性关节疾病. 这些发现为管理OA进展和疼痛提供了潜在的诊断和治疗目标.

关键词:
生物标志物 生物标志物免疫调节 免疫调节骨关节炎是一种骨关节炎.棕化代谢的代谢过程单细胞RNA测序的一个细胞.

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Methods of Classification and Identification01:28

Methods of Classification and Identification

Bacterial identification relies on a diverse array of techniques to classify and understand microorganisms, each tailored to uncover specific characteristics. Traditional morphological approaches, while still valuable, are limited for closely related or structurally simple organisms. Modern methods integrate biochemical, serological, genetic, and advanced molecular tools to achieve greater accuracy.Morphological and Biochemical TechniquesMorphological characteristics, such as cell shape and...