局部麻醉剂滥用角膜病变:一个被忽视的职业眼睛健康问题
Alireza Attar1, Alison L S Chiu2,3, Fatemeh Razmjooei4
1Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Journal of occupational medicine and toxicology (London, England)
|December 11, 2025
概括
局部麻醉剂的滥用会导致严重的视力丧失,特别是在职业环境中. 早期戒烟和支持性护理显著改善了这种疾病患者的视力敏度.
科学领域:
- 眼科医生 眼科 眼科
- 职业健康 职业健康 职业健康
背景情况:
- 局部麻醉剂滥用角膜病变是一种罕见但严重的眼睛损伤并发症.
- 经常出现眼睛损伤的职业环境,可能会导致麻醉药的自我施用.
- 这种情况可以导致不可逆转的视力丧失,如果不及时处理.
研究的目的:
- 评估局部麻醉药物滥用角质炎患者的临床发现和视觉结果.
- 识别与这种疾病相关的风险因素和常见病原体.
- 评估治疗干预措施的有效性.
主要方法:
- 在2023年3月至2025年3月期间,对被诊断患有局部麻醉滥用角质炎的患者进行了回顾性研究.
- 对人口统计,滥用持续时间,风险因素,微生物培养,治疗和视力敏度 (CDVA) 的分析.
- 住院时的CDVA和三个月的随访时间的比较.
主要成果:
- 包括13名患者 (14只眼睛),中位滥用持续时间为8.5天.
- 职业暴露 (接,金属研磨,建筑,管道) 是主要的风险因素.
- 从基线 (CDVA 中位数0.61 LogMAR) 到3个月的随访 (CDVA 中位数0.154 LogMAR) 视力敏度显著改善,12/14只眼睛达到≥5/10的斯内伦敏度.
- 并发症包括传染性角膜炎和一个角膜穿孔病例.
结论:
- 局部麻醉剂滥用角质皮质病是一种严重的公共卫生问题,具有严重的潜在并发症.
- 传染性角膜炎和角膜穿孔是与这种情况相关的风险.
- 公共教育,工作场所安全和更严格的法规对于预防至关重要.
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