GS4PB:一个R Shiny应用程序,以促进植物育种的基因组选择管道
Vishnu Ramasubramanian1, Cleiton A Wartha1, Lovepreet Singh1
1Department of Agronomy and Plant Genetics, University of Minnesota, Saint Paul, Minnesota, USA.
The plant genome
|December 12, 2025
概括
基因组选择工具有助于植物育种者有效地提高作物产量. 一个新的R Shiny应用程序,GS4PB,简化了基因组预测管道,使先进的技术可用于在育种计划中获得更快的遗传收益.
科学领域:
- 农业科学 农业科学
- 遗传学 是一个遗传学.
- 生物信息学是一种生物信息学.
背景情况:
- 在气候变化和资源限制的情况下,基因组学辅助育种对于提高作物产量至关重要.
- 由于缺乏全面的软件工具,中小型育种计划面临整合基因组选择的挑战.
- 弥合这一差距对于加速植物育种中的遗传收益至关重要.
研究的目的:
- 开发和展示一个集成的,开源的软件工具,以简化植物育种中的基因组预测管道.
- 为了降低进入先进的基因组预测技术的障碍.
- 证明开发的工具在增强遗传收益方面的有效性.
主要方法:
- 开发了一个R Shiny网络应用程序,GS4PB (植物育种基因组选择),集成开源工具.
- 该管道包括基因型数据处理 (过,归算),数据合并,环境学共变量收集,亲属估计,训练集优化和交叉验证.
- 实现对跨环境的单个/多个特征的基因组预测.
主要成果:
- GS4PB成功地整合了基因组预测管道的基本步骤.
- 一项比较表型和基因组选择的实验表明,基因组选择与表型选择相比,在推进繁殖线上表现得相当好.
- 该工具促进了先进的基因组预测方法的应用.
结论:
- 该GS4PB应用程序为植物育种计划中的基因组预测提供了一个用户友好的,集成的解决方案.
- 这种工具使先进的基因组选择技术获得民主化,赋予育种者加速遗传收益的权力.
- 广泛采用GS4PB可以为应对全球粮食生产挑战做出重大贡献.
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