相关实验视频

Updated: Jan 8, 2026

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
10:13

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses

Published on: May 6, 2019

9.4K

微调亲和度和间隔设计增强DLL3和BCMA CAR T细胞中的T细胞功效

Nicholas Mazzanti1,2, Ninkka Tamot1, Andrea Francese1

  • 1Therapeutics Discovery, Johnson & Johnson Innovative Medicine, Spring House, PA, USA.

mAbs
|December 12, 2025
PubMed
概括

优化仿真抗原受体 (CAR) T细胞疗法包括改进CAR设计. 具有中间间隔器的高亲和性CAR显示出优异的瘤杀伤和T细胞扩张对BCMA和DLL3标.

关键词:
亲密关系 (Affinity) 是一种关系.汽车 汽车 汽车 汽车汽车汽车的设计.仿制性抗原受体的复制性受体.空间空间域名空间域名

更多相关视频

Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography09:34

Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography

Published on: February 17, 2022

3.7K
Development and Functional Characterization of Murine Tolerogenic Dendritic Cells09:51

Development and Functional Characterization of Murine Tolerogenic Dendritic Cells

Published on: May 18, 2018

11.1K

相关概念视频

T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
14.6K
Diversity of Antigen Receptors01:28

Diversity of Antigen Receptors

Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
1.3K