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Updated: Jan 8, 2026

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis
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The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis

Published on: March 17, 2010

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药理动力学证据支持在患有蛋白C缺乏症的患者中皮下使用蛋白C缩剂

Zhaoyang Li1, Inmaculada C Sorribes2, Jennifer Schneider2

  • 1Takeda Development Center Americas, Inc., Cambridge, Massachusetts, United States.

TH open : companion journal to thrombosis and haemostasis
|December 12, 2025
PubMed
概括

皮下 (SC) 蛋白C缩剂的使用显示了严重先天性蛋白C缺乏症 (SCPCD) 的有希望的药理动力学 (PK) 数据. 模型模拟支持各种SC剂量方案,表明快速治疗度可能需要高负载剂量.

关键词:
人口的药理动力学蛋白质C度缩物蛋白C缺乏症 蛋白C缺乏症替代疗法是一种替代疗法.皮下注射 皮下注射 皮下注射

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