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Updated: Jan 8, 2026

Native Polyacrylamide Gel Electrophoresis Immunoblot Analysis of Endogenous IRF5 Dimerization
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在系统性自身免疫性疾病中对IRF介导的I型干扰素信号的TRIM21调节

Kailai Panlu1, Yihan Wang2, Xinchao Zhu1

  • 1The Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.

Frontiers in immunology
|December 12, 2025
PubMed
概括

三方基因含蛋白21 (TRIM21) 调节I型干扰素信号传递,对免疫平衡至关重要. 反-TRIM21抗体可以破坏这一过程,导致自身免疫性疾病和慢性炎症.

关键词:
在IRF家族中,IRF是最重要的.在 TRIM2121 中.自身免疫性疾病 自身免疫性疾病这是一种I型干扰子.无处不在的化

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