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Updated: Jan 8, 2026

LDL Cholesterol Uptake Assay Using Live Cell Imaging Analysis with Cell Health Monitoring
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LDL Cholesterol Uptake Assay Using Live Cell Imaging Analysis with Cell Health Monitoring

Published on: November 17, 2018

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在STAT5B SH2域中与疾病相关的突变重新编程肝脏胆固醇和脂质代谢

Hye Kyung Lee1, Maxim Pyatkov2, Oksana Gavrilova3

  • 1Section of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, Maryland 20892, USA.

bioRxiv : the preprint server for biology
|December 12, 2025
PubMed
概括

通过STAT5B变体改变生长激素 (GH) 信号影响肝脏代谢和胰岛素敏感性. 功能增强的STAT5B增强了脂质积累和女性化的男性肝脏基因表达.

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Analysis of Liver Microenvironment During Early Progression of Non-Alcoholic Fatty Liver Disease-Associated Hepatocellular Carcinoma in Zebrafish09:27

Analysis of Liver Microenvironment During Early Progression of Non-Alcoholic Fatty Liver Disease-Associated Hepatocellular Carcinoma in Zebrafish

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Hyperlipidemia, a medical condition often referred to as high cholesterol, is characterized by abnormally elevated levels of lipids in the bloodstream. When present in excess, these lipids, specifically cholesterol and triglycerides, can lead to serious health complications, often involving cardiovascular diseases. Illnesses like atherosclerosis, heart attacks, and pancreatitis have all been linked to untreated hyperlipidemia. This means controlling and regulating cholesterol and triglyceride...
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