维生素D水平与尿路感染之间的关联
Masoumeh Piyadah Kouhsar1, Morteza Alijanpour2, Mohammad Pournasrullah3
1Student Research Committee, Babol University of Medical Sciences, Babol, Iran.
Caspian journal of internal medicine
|December 12, 2025
概括
患有尿路感染 (UTI) 的儿童的维生素D水平明显降低. 查和补充维生素D可能有助于预防尿路感染,并改善儿科患者的治疗结果.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 内分泌学 在内分泌学.
背景情况:
- 尿路感染 (UTI) 在儿童中很常见.
- 维生素D缺乏与各种感染有关,包括尿路感染.
- 这项研究研究了儿科患者血清维生素D和尿路感染之间的关联.
研究的目的:
- 评估血清维生素D水平与儿童尿路感染之间的关联.
- 为了比较患有和没有尿路感染的儿童的维生素D水平.
主要方法:
- 一项涉及阿米尔·科拉儿童医院120名儿童 (2-18岁) 的病例控制研究.
- 60名患有尿路感染的儿童 (病例) 和60名健康儿童 (对照).
- 通过ELISA测量血清维生素D水平;使用SPSS v.26.6.进行统计分析.
主要成果:
- 与对照组 (37.91±12.18 ng/mL) 相比,患有尿路感染的儿童的血清维生素D水平明显较低 (17.70±8.35 ng/mL) (P<0.001).
- 皮叶龙炎与严重的维生素D缺乏症相关 (P=0.02).
- 3-5岁的女性儿童患维生素D缺乏症的风险较高,但年龄和性别并不是总体上重要的因素.
结论:
- 维生素D缺乏与儿童的尿路感染显著相关.
- 维生素D对尿路感染起着免疫保护作用.
- 查和补充维生素D可能是儿童尿路感染的有价值的预防策略.
相关概念视频
Urinary Tract Infection II: Pathophysiology
530
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
530
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
230
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
230
Urinary Tract Infection I: Introduction
512
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
512
Urinary Tract Calculi I: Introduction
377
Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
377
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
349
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
349
Urinary Tract Calculi IV: Nutrition Therapy and Prevention
339
Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
339


