低血压患者神经症状的危险因素:一个回顾性队列研究
Akira Nakamura1, Takashin Nakayama1, Tatsuhiko Azegami1
1Division of Nephrology, Endocrinology, and Metabolism, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Clinical kidney journal
|December 12, 2025
概括
严重的低血压可能会导致神经系统症状. 低血清,低血清和急性或不确定的发作独立预测这些症状,指导临床评估和管理.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 神经学 神经学
- 内部医学 内部医学
背景情况:
- 低血症是一种常见的电解质疾病,具有潜在的严重的神经后果.
- 预测严重低血症的神经干预的预测因素还没有得到很好的定义.
- 这项研究调查了血清含量低的患者的神经症状相关的因素.
研究的目的:
- 确定严重低血症患者神经症状的独立预测因子.
- 为临床实践提供有关低血的评估和管理的信息.
- 为了改善患有低血血症神经并发症的患者的治疗结果.
主要方法:
- 对834名患有严重低血症 (血清≤120mEq/L) 的患者进行了回顾性队列研究.
- 神经系统症状定义为吐,昏昏欲睡,发作,昏迷或心肺骤停.
- 用于评估风险因素的多变量逻辑回归分析.
主要成果:
- 在26%的患者中存在神经症状.
- 低血清 (OR 1.53) 和低血清<115 mEq/L (OR 2.23) 独立地与神经症状相关.
- 与慢性发病相比,急性 (OR 3.92) 和不确定的 (OR 2.05) 发病模式也是显著的预测因素.
结论:
- 低血清,低血清和发病模式是严重低血症神经症状的独立预测因素.
- 识别这些风险因素可以进行有针对性的评估和管理.
- 个性化治疗策略对于严重低血症患者的良好结果至关重要.
相关概念视频
Neural Regulation
43.0K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
43.0K
Hypertension III: Clinical Manifestations and Diagnostic Studies
442
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
442
Regulation of Water Intake
2.6K
Osmolality refers to the number of solute particles per kilogram of solvent in a solution. Plasma osmolality specifically indicates the total number of solute particles per kilogram of water in blood plasma. This value reflects the body's hydration status and is tightly regulated through mechanisms controlling water intake and output. While water consumption is a conscious decision, the body has intrinsic regulatory systems to maintain fluid balance. Dehydration, a state of water deficit...
2.6K
Disorder of Water Balance
2.3K
Water balance disorders are medical conditions that occur when there is a deviation from the body's water volume or osmolarity, disrupting normal homeostasis and leading todehydration, hypotonic hydration, hyperhydration, edema, or water intoxication.
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
2.3K
Disorders of the Nervous Tissue
2.5K
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
2.5K
Chronic Kidney Disease II: Clinical Manifestations
522
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
522


