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开发pyrazole-oxadiazole结合物作为强大的抗结核药物:一种in silico和in vitro方法

Sethu Arun Kumar1, Gurdayal Besra2, Sarah Batt2

  • 1Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research Sri Shivarathreeshwara Nagara Mysuru-570015 India gvpujar@jssuni.edu.in.

RSC medicinal chemistry
|December 12, 2025
PubMed
概括

新的pyrazole-oxadiazole化合物通过潜在地准Mycobacterium tuberculosis中的多种机制,显示出强大的抗结核活性. 这些新型药物为开发针对这种持久性病原体的新药提供了有希望的途径.

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