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Updated: Jan 7, 2026

A Model of Chronic Nutrient Infusion in the Rat
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ERp46减轻了脂毒性ER压力,以保持β细胞中的GLUT2表达和胰岛素分泌

Danling Chen1, Xiaomin Chen1, Yuan Tian1

  • 1Department of Endocrinology, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian 361003, P.R. China.

Biomedical reports
|December 12, 2025
PubMed
概括

胰腺内居住蛋白46 (ERp46) 保护胰腺β细胞免受2型糖尿病的脂毒性影响. 它通过支持AKT信号传递来保持葡萄糖转运体2 (GLUT2) 表达和胰岛素分泌.

关键词:
细胞内膜网膜中居住的蛋白质 46 46葡萄糖输送器 2 型脂肪毒性 脂肪毒性 脂肪毒性胰腺β细胞的功能蛋白质激酶B信号传递2型糖尿病是什么?

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