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孕产妇暴露于贝塔希斯和怀孕结果:一个回顾性队列研究

Doua Alsaad¹, Afif Ahmed¹, Wessam Elkassem¹

¹Pharmacy, Hamad Bin Khalifa Medical City, Hamad Medical Corporation, Doha, QAT.

|December 12, 2025

概括

这项研究发现,在怀孕期间暴露于贝塔希斯的婴儿中,不会增加重大出生缺陷的风险. 然而,需要更多的研究来确认贝塔希斯对孕妇的安全性.

科学领域:

产科和妇科产科和妇科
药理学药理学是指药理学的学科.
甲状腺学甲状腺学

背景情况:

贝塔希斯通常是安全的,但缺乏关于怀孕使用的数据.
贝塔希斯对怀孕的结果和产性风险没有评估.

研究的目的:

审查暴露于贝塔希斯的妇女怀孕结果.
为了确定在子宫内暴露于贝塔希斯的婴儿中主要发育不良的发生率和模式.

主要方法:

描述性的回顾性队列研究.
包括2020年4月至2022年3月期间处方贝塔希斯的孕妇.
随后的怀孕结果包括分娩,堕胎和婴儿随访.

主要成果:

分析了40名怀孕妇女的42个结果.
大多数妇女在怀孕的第一季度接受了高剂量的贝塔希斯 (48毫克).
没有观察到任何重大形;报告有五种轻微的形.

结论:

在子宫内暴露于贝塔希斯并没有增加重大先天性形的发生率.
小样本规模和回顾性设计限制了关于安全的最终结论.
建议在怀孕期间避免不必要的药物.

关键词:

贝塔希斯因 (betahistine) 是一种抗胰岛素.胎儿的胎儿是一个胎儿.怀孕怀孕怀孕怀孕怀孕在安全方面,安全是安全的.地震学是指地球上的物种.

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