糖尿病前期和男性性功能障碍之间的关联:更新的元分析
Saad Alshahrani1, Mohammed Alfozan1, Ashraf El-Metwally2
1Department of Surgery, Division of Urology, College of Medicine, Prince Sattam bin Abdulaziz University, Alkharj.
概括
糖尿病前期显著增加男性性功能障碍的风险. 与正常血糖水平相比,患有糖尿病前期男性患性功能障碍的可能性是2.5倍.
科学领域:
- 内分泌学 在内分泌学.
- 男人的健康 男人的健康
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 前糖尿病是一种日益增长的全球代谢障碍.
- 虽然其血管和代谢作用是已知的,但其与男性性功能障碍的联系尚不清楚.
研究的目的:
- 分析男性糖尿病前期和性功能障碍之间的关联.
- 通过元分析来总结现有证据.
主要方法:
- 在PubMed,Embase和Scopus的系统文献搜索.
- 十项涉及11000名参与者的观察性研究的元分析.
- 使用纽卡斯尔-太华尺度评估研究质量,使用埃格尔测试评估出版偏差.
主要成果:
- 糖尿病前男性的性功能障碍的几率是性功能障碍的2.50倍 (OR:2.50,95%CI:1.35-4.64).
- 观察到很高的异质性 (I2 = 87.9%).
- 根据GRADE方法,证据的质量通常很低.
结论:
- 患有糖尿病前期男性面临的性功能障碍的风险明显更高.
- 建议进行进一步的高质量的前性研究,以确认发现并调查机制.
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