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Updated: Jun 29, 2026

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes
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新型鲁福米辛"点击化学"同类与Mtb ClpC1的独特相互作用和影响

Kiira Ratia, Shengnan Jin, Celerino Abad-Zapatero

  • 1Biophysics Core at Research Resource CenterUniversity of Illinois at Chicago, Chicago, Illinois 60607, United States.

Journal of medicinal chemistry
|December 12, 2025
PubMed
概括

新的二度鲁福米辛类似物通过破坏蛋白质平衡来有效地向Mycobacterium tuberculosis (Mtb). 这些化合物表现出强烈的抗Mtb活性和长时间的结合,为抗结核病提供了新的策略.

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