甲状腺结节的后壁囊性形状可以预测良性吗?
Jean-Guillaume Marchand1,2, Marie Bienvenu-Perrard2,3, Agnes Rouxel2,4
1Thyroid and Endocrine Tumors Department, La Pitié-Salpêtrière Hospital, Sorbonne University, GRC No. 16, Paris, France.
European thyroid journal
|December 12, 2025
概括
在EU-TIRADS 4甲状腺结节中,背壁囊性数字 (BWCF) 表明恶性瘤风险低,类似于EU-TIRADS 3结节. 将BWCF与微化区分开来,可以改善风险分层,并可能为未来的甲状腺结节指南提供信息.
科学领域:
- 甲状腺成像和诊断
- 基于超声波的风险分层.
- 精细针吸收 (FNA) 细胞学
背景情况:
- 欧洲甲状腺协会 (ETA) 2023年指导方针将超声波斑点分为彗星尾部文物,后壁囊形象 (BWCF) 和微化.
- BWCF通常被认为是良性的,但现有的文献对这一假设提供了有限的支持.
研究的目的:
- 为了确定EU-TIRADS 4甲状腺结节是否具有BWCF,与没有BWCF的甲状腺结节相比,恶性瘤的风险降低.
- 为了比较EU-TIRADS 4结节的恶性瘤风险与BWCF与EU-TIRADS 3结节的恶性瘤风险.
- 在这些群体中评估不确定的和良性细胞学率.
主要方法:
- 在精细针吸收之前,四名医生预计将150个甲状腺结节纳入.
- 分类为三组:50个EU-TIRADS 4个节点与BWCF,50个EU-TIRADS 4个节点没有BWCF,50个EU-TIRADS 3个节点.
主要成果:
- 在没有BWCF和BWCF的EU-TIRADS 4结节之间观察到恶性瘤风险的显著差异 (P < 0.001).
- 带有BWCF的EU-TIRADS 3和EU-TIRADS 4结节显示出贝塞斯达II细胞学的高率 (分别为94%和82%),与没有BWCF的EU-TIRADS 4结节 (26%) 相反.
- 贝塞斯达III-IV细胞学在没有BWCF的EU-TIRADS4结节 (62%) 中比具有BWCF (18%) 或EU-TIRADS3结节 (6%) 的结节更为普遍.
结论:
- 在EU-TIRADS 4节点中的BWCF与恶性瘤的低风险有关,与EU-TIRADS 3节点相比较.
- 区分BWCF与其他超声波焦点,如微化,对于准确的风险分层至关重要.
- 承认BWCF可能会支持更高的FNA门,并应在未来的I-TIRADS指南中考虑.
相关概念视频
Sensitivity, Specificity, and Predicted Value
1.2K
In healthcare diagnostics, laboratory tests play a crucial role in identifying and diagnosing a wide range of medical conditions. However, interpreting test results is not always straightforward. An abnormal test result does not always confirm the presence of a disease, just as a normal result does not guarantee its absence. To assess the reliability of these diagnostic tools, healthcare practitioners rely on two key statistical indicators: sensitivity and specificity.
Sensitivity is the...
Sensitivity is the...
1.2K
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
370
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
370
The Thyroid Gland
6.5K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
6.5K


