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DNA双链断裂修复:SUMO信号中的特异性和复杂性的模型

Jai S Bhachoo1, Alexander J Garvin1

  • 1SUMO Biology Lab, School of Molecular and Cellular Biology and Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, U.K.

Essays in biochemistry
|December 12, 2025
PubMed
概括

小型泛素类修饰剂 (SUMOs) 调节DNA双链断裂 (DSB) 修复. 不同的SUMO对应物通过不同的信号通路实现特定的细胞功能和修复结果.

关键词:
合成和修复DNA的过程.这就是SUMOylation的作用.在这种情况下,染色染色素无处不在的素连接酶.无处不在的蛋白质酶体系统无处不在的信号传输

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