美国退伍军人中燃烧坑烟雾暴露和睡眠呼吸暂停:一项回顾性队列研究
Ritwick Agrawal1, Javad Razjouyan2,3,4,5, Danielle R Glick5,6
1Lung Institute, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Huntington, NY.
Medical care
|December 12, 2025
概括
燃烧坑烟雾暴露 (BPSE) 并没有增加睡眠呼吸暂停 (SA) 的患病率,但与退伍军人早期的SA诊断有关. 对于那些具有显著BPSE的人来说,建议对SA进行早期查.
科学领域:
- 环境健康 环境健康
- 呼吸系统医学 呼吸系统医学
- 军人卫生保健 军人卫生保健
背景情况:
- 燃烧坑烟雾暴露 (BPSE) 是退伍军人的长期健康问题.
- BPSE和睡眠呼吸暂停 (SA) 之间的联系需要进一步调查.
研究的目的:
- 检查BPSE和SA流行率和诊断时间之间的关联.
- 分析BPSE对退伍军人的心肺呼吸系统疾病的影响.
主要方法:
- 使用VHA EMR和AHOBPR数据进行回顾性队列研究.
- 按持续时间分类的BPSE;根据AHI分类的SA严重性.
- 逻辑回归和考克斯模型调整了混因子.
主要成果:
- 在调整后,没有发现BPSE和SA流行率之间的显著关联.
- 具有最高BPSE四分位数的退伍军人更早诊断出SA (中位数为8.8年).
- 在最高BPSE四分位数中,早期SA诊断的调整后危险比为1.16 (95%CI:1.10,1.22).
结论:
- BPSE与早期的SA诊断有关,而不是增加患病率.
- 呼吸道炎症或增加医疗保健利用率可能解释早期诊断.
- 建议对BPSE严重影响的退伍军人进行早期SA监测.
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