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Updated: Jan 8, 2026

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
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Published on: November 11, 2016

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DEC1调节人类β细胞的功能成熟和昼夜节律.

Sam Preza1, Bliss Zheng2, Zihan Gao1

  • 1Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA; Chronobiology and Sleep Institute, and Institute for Regenerative Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA; Institute for Diabetes, Obesity and Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

Cell reports
|December 12, 2025
PubMed
概括

一种关键蛋白DEC1对于使干细胞衍生小岛器官成熟和功能为糖尿病治疗至关重要. 它同步昼夜时钟,改善胰岛素分泌和葡萄糖反应.

关键词:
三维有机物质 3D有机物质培训班:发展生物学CP:代谢过程中的代谢.在SC-β细胞成熟过程中.细胞替代疗法是一种细胞替代疗法.昼夜时钟是生物周期的时间表.葡萄糖刺激的胰岛素分泌物代谢同步的代谢同步在β细胞的能量方面.

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