在儿童急性复发性和慢性胰腺炎的疼痛中通过互联网提供认知行为干预:多中心随机对照试验
Tonya M Palermo1,2, Rui Li1, Chuan Zhou1
1Center for Child Health, Behavior and Development, Seattle Children's Research Institute.
Pancreas
|December 12, 2025
概括
这项研究发现,通过互联网提供的认知行为疗法 (CBT) 对儿科胰腺炎疼痛是可行的和可以接受的. 然而,在CBT和疼痛教育组之间没有观察到疼痛或健康结果的显著差异.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 疼痛管理 疼痛管理
- 数字健康干预措施 数字健康干预措施
背景情况:
- 儿科急性复发性 (ARP) 和慢性胰腺炎 (CP) 导致显著的腹痛,负担和医疗费用.
- 心理干预对其他儿科腹痛疾病有希望,但尚未对胰腺炎进行研究.
- 通过互联网提供的认知行为疗法 (CBT) 提供了一种可扩展的方法来应对这些挑战.
研究的目的:
- 评估通过互联网提供的CBT对儿科胰腺炎的可行性,可接受性和初步疗效.
- 评估疼痛干扰,焦虑,抑郁,活动限制和生活质量的改善.
- 为了比较互联网提供的CBT (WebMAP-CP) 与互联网提供的疼痛教育 (WebED).
主要方法:
- 一个随机的安慰剂控制的多中心试验招募了90名青少年 (年龄10-19岁) 患有ARP或CP.
- 参与者被随机分配到WebMAP-CP (n=46) 或WebED (n=44).
- 治疗前进行了评估,治疗后3个月和6个月进行了评估.
主要成果:
- 在两组中,强烈的治疗参与 (超过6/8个模块完成) 证明了高可行性.
- 与WebED相比,WebMAP-CP组的治疗可接受性显著更高.
- 在疼痛或健康结果方面,没有发现群体之间的统计学上显著差异.
结论:
- 这是第一个评估儿童胰腺炎疼痛的互联网交付CBT的试验,显示出强大的可行性和可接受性.
- 报名不足限制了该研究的统计能力.
- 以更大的样本大小进行未来的研究是有必要的,以这些发现为基础.
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