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Updated: Jan 8, 2026

Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking
11:33

Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking

Published on: December 17, 2013

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SPNS1是EV-A71的一个重要细胞因子,通过作为病毒口袋因子的载体来起作用

Yu-Zhi Fu1,2, Fang-Fang Luo1,2, Liu Yang1,2

  • 1State Key Laboratory of Virology and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.

Proceedings of the National Academy of Sciences of the United States of America
|December 12, 2025
PubMed
概括

脂转运体1 (SPNS1) 对于肠道病毒A71 (EV-A71) 感染至关重要,通过携带一个口袋因子来促进病毒脱皮. 在动物模型中,SPNS1缺乏会降低病毒载量和疾病严重程度.

关键词:
这就是SPNS1的意义.人类肠道病毒A71钱包因素是一个口袋因素.没有去除涂层.

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