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实时监测全血中药物释放的情况,基于光学干涉计

Nian Ding1, Na Ni1, Xinyu Yang1

  • 1School of Pharmacy, Jiangsu Ocean University, Lianyungang, Jiangsu 222005, China.

Analytical chemistry
|December 12, 2025
PubMed
概括

这项研究提出了一种新的方法,用于使用功能化合晶体 (SCC) 干扰度层实时监测多克索鲁比辛化释放. 该系统通过测量光学厚度的变化来跟踪药物释放,为先进的药物输送系统提供了洞察力.

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Measurement of Bioavailability: Pharmacodynamic Methods01:20

Measurement of Bioavailability: Pharmacodynamic Methods

Pharmacodynamic methods provide insights into a drug's effects on physiological processes over time and play a crucial role in understanding bioavailability and therapeutic efficacy. These methods can be broadly classified into acute pharmacological and therapeutic response approaches, each with distinct mechanisms and applications.The acute pharmacological response method directly correlates a drug's physiological effects, such as ECG or pupil diameter changes, to its time course in the body.
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