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注射器残留分析在识别性化药物使用实践中消耗的物质方面的作用

Carlos Pernas-Fraguela¹, Rosario Rodil¹, José Benito Quintana¹

¹Aquatic One Health Research Center (ARCUS) & Department of Analytical Chemistry, Nutrition and Food Science, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.

Journal of pharmaceutical and biomedical analysis

|December 12, 2025

概括

化学性爱,特别是猛烈性爱,涉及在性活动期间使用毒品. 注射器残留物分析准确地确定了丁作为最常见的药物,揭示了这一群体的消费趋势.

科学领域:

法医化学法医化学
药物成科学药物成科学
公共卫生公共卫生

背景情况:

化学性爱,通常涉及静脉注射药物使用 (冲击),在与男性发生性关系的男性中很普遍.
准确识别化学性爱中使用的物质对于减少危害和公共卫生干预至关重要.
注射器残留物分析为客观物质检测提供了一种新的方法,但其在chemsex群体中的应用以前尚未被探索.

研究的目的:

调查化学性人口中特定的药物消费模式,重点关注击败实践.
评估注射器残留分析对准确识别化学性爱期间使用的物质的有用性.
在这个人口群体中检测物质使用的时间趋势.

主要方法:

在马德里的一个药物成援助中心从从事化学性行为的个人那里收集了注射器样本 (n=122).
使用甲醇冲洗提取物质,然后使用液态染色学加上高分辨率质谱法 (LC-HRMS) 进行分析.
数据分析采用了可疑选方法来识别和量化检测到的化合物.

主要成果:

卡西诺因是最常检测到的药物类别 (99%),其次是安非他命和可卡因.
甲丁是最常见的甲丁,其他已识别的化合物包括甲基甲丁,丁和N,N-dimethylpentylone.
在不同的抽样活动中观察到物质检测的显著时间趋势,反映了市场动态.

结论:

注射器残留物分析提供了准确的洞察力,对药物消费在冲击期间,可能与自我报告的数据不同.
该研究确定了特定的甲基和使用时间模式,为有针对性的干预提供了有价值的数据.
调查结果强调,需要针对性减少危害的战略,以应对化学性社区不断变化的毒品环境.

关键词:

卡西诺尼斯 (Cathinones) 是一种的物质.化学性爱是一种性行为.减少伤害减少伤害高分辨率的质谱仪.

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