在两个潜在的队列中,慢性孤独和发生的慢性肺部疾病
Bo Yan1, Yuechang Li1, Haoyu Wu2
1Institute of Social Medicine, School of Medicine, Zhejiang University, 866 Yuhangtang Road, Xihu District, Hangzhou 310058, China.
Archives of gerontology and geriatrics
|December 12, 2025
概括
慢性孤独会增加患慢性肺部疾病的风险. 管理孤独感可能有助于预防这些情况.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 老年学是一门学科.
背景情况:
- 孤独是慢性肺部疾病的一个已知的危险因素.
- 以前的研究集中在基线孤独,而不是随时间变化.
研究的目的:
- 检查慢性孤独与发生慢性肺部疾病之间的关联.
- 调查孤独状态的变化如何影响肺部疾病风险.
主要方法:
- 采用美国健康与退休研究 (HRS) 和中国健康与退休纵向研究 (CHARLS) 数据的多队列研究.
- 对45岁以上 (中国) 和50岁以上 (美国) 参与者的孤独变化模式 (稳定低,低高,高低,稳定高) 的分析.
- 考克斯比例危害回归模型用于估计慢性肺病风险.
主要成果:
- 18,031人分析了孤独的变化和肺部疾病风险.
- 在"低-高"",高-低"和"稳定高"孤独群体中观察到慢性肺部疾病的风险增加,而在两个队伍中"稳定低"相比.
- 报告了每个组和队列的特定危险比率 (HR) 和置信区间 (CI),表明了重要的关联.
结论:
- 慢性孤独与患慢性肺部疾病的风险更高有关.
- 孤独状态的变化,包括增加或持续高水平,与疾病风险增加有关.
- 旨在减少或管理孤独的干预措施可能对预防慢性肺病至关重要.
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