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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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以 (II),铜 (II) 和 (II) 的π扩展的希夫基复合体准非正规DNA:对G-四重复合结合模式的洞察

Luisa D'Anna1, Silvia Lo Iacono1, Laura Marretta1

  • 1Dipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche, Università degli Studi di Palermo, 90128 Palermo, Italy.

Journal of inorganic biochemistry
|December 12, 2025
PubMed
概括

新的铜 (II) 金属复合物与甲桥接的希夫基联体显示出强大的G-四重复 (G4) DNA结合和稳定. 扩展的连接体框架通过改善DNA相互作用和选择性来增强抗癌药物潜力.

关键词:
铜铜 铜铜 铜铜FRET DNA 化测定试验在G-quadruplex中使用.金属复合物的金属复合物尼克尔 尼克尔是什么意思可以在中找到.

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