改进的饮食工具和点滴尿收集的结合:用于估计每日摄入量的改进方法
Eirini D Basdeki1, Kalliopi Karatzi2, Vrettos Moulos3
1Cardiovascular Prevention & Research Unit, Clinic & Laboratory of Pathophysiology, Department of Medicine, National and Kapodistrian University of Athens, Greece.
Nutrition (Burbank, Los Angeles County, Calif.)
|December 12, 2025
概括
一个新的,更短的食物频率调查问卷 (FFQ-Na-2) 与点性泌尿方法相结合,显示出评估每日摄入量的前景. 这种改进的方法为临床监测提供了更实用的方法.
科学领域:
- 营养科学 营养科学
- 生物化学 生物化学
- 公共卫生 公共卫生
背景情况:
- 准确评估每日 (Na) 摄入量对于管理心血管健康至关重要.
- 目前用于Na评估的饮食和点尿方法在准确性方面存在局限性.
- 24小时尿液Na (24hUNa) 排泄是黄金标准,但对于常规临床使用来说很麻烦.
研究的目的:
- 通过缩短的食物频率问卷 (FFQ-Na) 来提高其可用性.
- 评估缩短FFQ-Na与点性尿道方法 (sUMs) 的组合,以改善每日Na摄入量的评估.
- 确定这些改进方法在临床实践中的可行性.
主要方法:
- 一项涉及219名完成FFQ-Na的参与者的横截面研究提供了两个24hUNa采集和一个点滴尿样.
- 人工智能被用来开发FFQ-Na的更短版本,通过识别具有低附加值的问题.
- 使用接收器运行特征 (ROC) 曲线分析和回归模型 (Tanaka,Toft) 来评估24hUNa的预测性能.
主要成果:
- 开发了三个较短的FFQ-Na版本:FFQ-Na-1 (43个问题),FFQ-Na-2 (37个问题) 和FFQ-Na-3 (29个问题),缩短了完成时间.
- 与Tanaka或Toft方程相结合的FFQ-Na-2显示了与24hUNa.相比的中等预测能力 (r2 = 0.404-0.411).
- ROC分析显示,FFQ-Na-2在检测高每日Na摄入量 (>3g/d) 的曲线下面积 (0.721),灵敏度 (0.628) 和特异性 (0.839) 中具有最高的区域.
结论:
- 当FFQ-Na-2与点性泌尿方法 (Tanaka或Toft方程) 一起使用时,它为评估日常饮食摄入量提供了一种可行和有前途的方法.
- 与之前的代和独立的sUMs相比,这种组合方法提供了更好的可用性和准确性.
- 建议进行进一步的研究和验证,以优化和在临床环境中实施这种方法来监测摄入量.
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