相关实验视频

Updated: Jan 8, 2026

Surgical Treatment of an Endolymphatic Sac Tumor

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

中子捕获疗法用于不可切除的残留外部听道癌

Hideto Shigemi¹, Yoshinori Kadowaki¹, Teruhito Aihara²

¹Oita University Faculty of Medicine, Department of Otolaryngology Head and Neck Surgery, Idaigaoka 1-1, Hasama-machi, Yufu city, Oita 879-5593 Japan.

Auris, nasus, larynx

|December 12, 2025

概括

中子捕获疗法 (BNCT) 有效地治疗了一名患者的残留中耳癌. 虽然发生了晚期不良事件,但患者保持了良好的生活质量,证明了BNCT.

科学领域:

在瘤学瘤学.
辐射瘤学辐射瘤学
医学物理医学物理

背景情况:

中子捕获疗法 (BNCT) 是针对不可切除癌症的向辐射疗法.
在日本,BNCT目前仅针对不可切除的头癌 (HNC) 获得医疗保险.
对于个别BNCT病例的详细临床结果,特别是对于外部听道癌,没有充分的记录.

研究的目的:

报告一个用BNCT治疗不可切除的外部听道癌症的患者的详细临床过程和结果.
评估BNCT在常规治疗后的残留病变管理中的有效性和安全性.

主要方法:

一名59岁的男性患者患有右耳道状细胞癌,接受了BNCT治疗残留的中耳和前耳膜病变.
该患者此前曾接受过手术和化疗放射治疗.
随访包括临床评估和成像,以监测病变控制和不良事件.

主要成果:

在3年的随访中,BNCT实现了对中耳病变的局部控制.
耳前病变需要进行额外的外科切除.
晚期不良事件包括3级大脑辐射亡和皮肤疾病,但患者保持了生活质量和日常活动.

结论:

BNCT可能是不可切除的残留外部听道癌的可行的治疗选择,在中耳中实现长期的局部控制.
仔细监测晚期不良事件,如放射性亡,至关重要.
尽管有不良事件,但BNCT可能会保持患者的生活质量.

关键词:

中子捕获疗法中子捕获疗法大脑辐射死亡症.外部听觉通道癌瘤剩余的东西剩余的东西

更多相关视频

Author Spotlight: Optimizing EAS with Long Electrodes for Enhanced Cochlear Coverage and Hearing Preservation

Author Spotlight: Optimizing EAS with Long Electrodes for Enhanced Cochlear Coverage and Hearing Preservation

Published on: October 11, 2024

Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique

Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique

Published on: May 23, 2021

相关概念视频

Treatment Resistant Cancers

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...