中心和手臂压力:对老年人动脉硬性的影响
Sakar Gupta1, Timothy Hess2, Amy Hein2
1University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
American journal of hypertension
|December 12, 2025
概括
在老年人中,与中心血压相比,手臂血压 (BP) 高估了动脉硬度 (CAS). 这种差异在高血压患者中更为明显.
科学领域:
- 心血管研究的心血管研究.
- 老年医学 老年医学
- 血管生物学 血管生物学
背景情况:
- 动脉硬度 (CAS) 评估通常使用手臂血压 (BP) 作为中央BP的替代品.
- 这种做法尚未在老年人群中进行彻底的研究.
研究的目的:
- 评估在60岁及以上的成年人中计算CAS时使用手臂血压与中心血压的影响.
- 为了确定手臂血压是否在这个人群中高估了CAS.
主要方法:
- 招募了180名60岁以上的男性退伍军人.
- 通过超声波测量休息臂部和中心血压,以及动脉尺寸.
- 使用手臂和中央BP计算的CAS参数 (PEM,YEM,DC).
- 使用统计模型分析了与心血管风险因素的差异和关联.
主要成果:
- 在研究队列中,手臂缩血压明显高于中心血压.
- 与中央BP计算CAS的结果是,与使用手臂BP相比,Young弹性模量 (YEM) 和Peterson弹性模量 (PEM) 显著降低,延展系数 (DC) 较高.
- 没有高血压与PEM的差异较小相关,而年龄较大与DC的差异较大相关.
结论:
- 在老年人中,使用手臂血压和中央血压计算的CAS存在显著差异.
- 手臂血压倾向于高估CAS,特别是在高血压患者中.
- 这些发现强调了使用中央BP对于老年人群中准确的CAS评估的重要性.
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