持续反应抑制的双神经机制:右侧核控制和左侧自适应性支持
Liyue Lin1, Jiahe Sun1, Wei Xiong2
1School of Psychology, Research Center for Exercise and Brain Science, Shanghai University of Sport, Shanghai, China.
NeuroImage
|December 12, 2025
概括
持续的抑制对于行为控制至关重要,它涉及不同的神经网络,这些神经网络随着时间需求而变化. 这项研究揭示了大脑如何灵活地通过吸引大脑更广泛的区域来持续控制来管理停止反应.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 神经成像是一种神经成像.
背景情况:
- 适应性行为控制依赖于持续的抑制,但其神经基础尚不清楚.
- 了解持续抑制是解释复杂认知功能的关键.
研究的目的:
- 通过停止信号任务来研究持续抑制的神经机制.
- 为了区分支持持续与暂时抑制的神经系统.
- 探索时间需求如何影响抑制控制.
主要方法:
- 来自26名参与者的fMRI数据跨越了不同的停止信号延迟 (SSD).
- 序列选择性停止信号任务来评估行为动态.
- 激活概率估计 (ALE) 64项先前研究的元分析.
主要成果:
- 响应时间随着SSD的增加而减少;抑制执行时间显示了反转的U形.
- 持续的抑制比暂时的抑制招募了更广泛的双边网络 (额前,顶部,皮层下).
- 确定了一种双重机制的网络:早期的竞争涉及双边区域,晚期的停止依赖于右主导的前额线路.
结论:
- 持续抑制是一种具有动态时间组织的独特控制过程.
- 大脑在不断变化的时间需求下使用灵活的双机制网络进行抑制控制.
- 这些发现为理解神经调节行为提供了一个新的框架.
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