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通过促进线粒体功能障碍,CPT1A会加剧trastuzumab引起的心脏毒性

Yukun Liu1, Binjie Chen2, Hanqing Li3

  • 1Department of Breast Surgery, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, China; Department of Breast Surgery, Qingdao Central Hospital, University of Health and Rehabilitation Sciences(Qingdao Central Hospital), China.

International journal of biological macromolecules
|December 12, 2025
PubMed
概括

研究人员确定了CPT1A作为关键的线粒体基因,与乳腺癌患者的Trastuzumab诱导心脏毒性 (TIC) 有关. 这一发现可能会导致在HER2向治疗期间预防心脏损伤的新策略.

关键词:
生物标志物 生物标志物CPT1A 一个问题.心脏有毒性 - 心脏有毒性机器学习是机器学习.这就是Trastuzumab.

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