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Updated: Jan 8, 2026

Residue-Specific Exchange of Proline by Proline Analogs in Fluorescent Proteins: How "Molecular Surgery" of the Backbone Affects Folding and Stability
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Published on: February 3, 2022

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在可电离性脂质中通过与硫的替代重新编程mRNA递送热带

Xing Duan1, Hai Huang1, Shengbin Liu1

  • 1Department of Critical Care Medicine, Frontiers Science Center for Disease-related Molecular Network, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.

Advanced materials (Deerfield Beach, Fla.)
|December 12, 2025
PubMed
概括

一种新的-硫 (N-to-S) 脂质修饰策略将信使RNA (mRNA) 疗法从肝脏重定向到肺部和脏等其他器官. 这种方法增强了治疗应用和抗瘤效果,同时确保了安全性.

关键词:
免疫疗法 免疫疗法这是mRNA疫苗.选择性器官输送提供器官.硫脂化物 硫脂化物毒性的毒性 毒性的毒性

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