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Updated: Jan 8, 2026

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies
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综合性多组学分析确定了对炎症性肠病的基因支持的可用药物标

Si-Chun Gu1, Si-Lu Zeng1, Wei Zhang1

  • 1Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 725 South Wanping Road, Shanghai 200032, China.

Journal, genetic engineering & biotechnology
|December 12, 2025
PubMed
概括

这项研究确定了Thrombospondin-3 (THBS3),RORC和TNFRSF25作为炎症性肠病 (IBD) 的潜在药物标. 预测了候选药物,为IBD治疗提供了新的治疗途径.

关键词:
药物耐药性基因是可以产生药物的基因.炎症性肠病是一种炎症性肠病.多个omics的多个omics.基于总结数据的门德尔随机化.

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