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Updated: Jan 8, 2026

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells
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使用遗传密码扩展和点击化学,同时可视化β-catenin明显的翻译后修改状态.

Christer Abou Anny1, Sébastien Nouaille2, Isabelle Huvent1

  • 1Univ. Lille, CNRS, UMR 8576 - UGSF - Unité de Glycobiologie Structurale et Fonctionnelle, F-59000, Lille, France.

Chembiochem : a European journal of chemical biology
|December 12, 2025
PubMed
概括

研究人员开发了一种新方法,可视化活细胞中单个蛋白质的不同翻译后修饰 (PTM) 状态. 这种技术允许在癌症研究中研究蛋白质调节和稳定性.

关键词:
然后点击化学.遗传密码扩展 扩展 遗传密码后翻译修改后的修改.蛋白质成像技术 蛋白质成像这是β-catenin.

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