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Updated: Jan 8, 2026

Perforated Patch-clamp Recording of Mouse Olfactory Sensory Neurons in Intact Neuroepithelium: Functional Analysis of Neurons Expressing an Identified Odorant Receptor
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Perforated Patch-clamp Recording of Mouse Olfactory Sensory Neurons in Intact Neuroepithelium: Functional Analysis of Neurons Expressing an Identified Odorant Receptor

Published on: July 13, 2015

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一个表观遗传抑制剂TRIM66决定了单一的嗅觉受体表达,神经活动和嗅觉行为

Hongqiang Bao1,2, Rong Liu1,2, Yalei Kong1,2

  • 1Department of Otolaryngology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Nature communications
|December 12, 2025
PubMed
概括

研究人员确定TRIM66是嗅觉受体基因选择中的关键抑制剂. 在嗅觉感官神经元 (OSN) 中删除Trim66会破坏嗅觉受体基因的沉默,影响嗅觉处理和行为.

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