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Updated: Jan 8, 2026

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肝脏特异性氧酶-1通过肝细胞癌的代谢重编程减轻调节性T细胞驱动的免疫抑制

Zhou Lu1,2,3, Huanchen Shi4, Rongshan Gao4

  • 1Institute of Clinical Sciences, Zhongshan Hospital, Fudan University, Shanghai, China. lu.zhou1@zs-hospital.sh.cn.

Nature communications
|December 12, 2025
PubMed
概括

氧酶-1 (PON1) 通过调节新陈代谢和减少免疫抑制来抑制肝癌. 增强PON1在治疗肝细胞癌 (HCC) 和改善免疫疗法反应方面表现有前途.

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