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功能化核酸:作为生物材料的生物结合物的合成和净化策略

Nico Alleva1, Jian Zhang1, David Y W Ng1

  • 1Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.

Small (Weinheim an der Bergstrasse, Germany)
|December 13, 2025
PubMed
概括

本综述探讨了制造和净化核酸结合物的方法,这些结合物对于先进的生物医学和材料科学应用至关重要. 成功的策略可以产生高纯度的材料,用于各种用途.

关键词:
DNA纳米技术 DNA纳米技术然后点击化学.混合生物材料混合生物材料核酸生物结合物 核酸生物结合物净化技术 净化技术固相合成的固相合成方法提供治疗性治疗.

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Proteins are involved in several cellular processes and biochemical reactions. Analyzing a specific protein of interest requires it to be isolated from the other proteins in the cell. This is achieved by overexpressing the specific gene in a suitable host to produce large quantities of the target protein. A tag or label is recombined with the gene to produce a fusion protein containing the target protein and the tag. The tags on these fusion proteins can then be used for easy detection and...
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