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Updated: Jan 8, 2026

Efficient Gene Knockdown in the Liver via Intrasplenic Injection of Adeno-Associated Virus Serotype 8 (AAV8)-Delivered Small Hairpin RNA
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Efficient Gene Knockdown in the Liver via Intrasplenic Injection of Adeno-Associated Virus Serotype 8 (AAV8)-Delivered Small Hairpin RNA

Published on: November 1, 2024

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通过m6A调节的let-7c-5p/LIN28B轴,NRAV促进了HCC的干度

Yuhang Chen1,2, Suoyi Dai1,2, Liping Zhuang1,2

  • 1Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.

Cancer gene therapy
|December 13, 2025
PubMed
概括

研究人员发现了一种新的分子途径,涉及NRAV长非编码RNA (lncRNA),它驱动肝癌 (HCC) 的干细胞. 这种由m6A修饰调节的NRAV-let-7c-5p-LIN28B轴,为肝癌治疗提供了潜在的治疗标.

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