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通过NKG2D特异性CAR巨细胞的协同天生的适应性免疫力驱动肝细胞癌的持久缓解

Zihao Zhao1,2, Wenjing Zheng2, Yang He3

  • 1Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

Molecular cancer
|December 13, 2025
PubMed
概括

针对NKG2D连体的工程化化学原体受体巨细胞 (CAR-Ms) 通过增强细胞和免疫激活,有效地消除肝细胞癌 (HCC). 与抗PD-L1疗法的结合进一步改善了HCC清除和生存率.

关键词:
化学抗原受体巨细胞肝细胞癌是肝细胞癌.在 NKG2D 连接物中,NKG2D 连接物具有发细胞症 (phagocytosis) 是一种致死细胞的发生.瘤微环境是一个微环境.

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